Episodes

In this episode I am doing something a little different. Everything I usually talk about goes in your body. Today I am talking about what goes on your body, specifically the ingredients that researchers have actually studied for aging skin and why pharmaceutical grade standards matter just as much for your skincare as they do for everything else. I also address something I think will make everything I cover on this podcast make a lot more sense. Why the delivery method always follows the science...

You put in the work. You hit your goal on a GLP-1. Now what. This episode picks up where episode 22 left off and answers the question I get asked a lot. If you have not listened to episode 22 — GLP-1s. What You Need to Know While You Are On One. I recommend starting there first. Today I am talking about what actually happens after you hit your goal. And I am not going to sugarcoat it. The research is clear that coming off a GLP-1 is not easy and weight regain is real, fast, and driven by biology...

I have done a lot of episodes on individual peptides. And I have talked before about why your body stops responding after 40. But I have never connected all of those dots in one place. Until now. In this episode I walk you through exactly what the research shows is happening in your body after 40, the specific biological changes that are documented and real, and for each one I tell you which peptide I have covered on this podcast that addresses that specific thing. Muscle loss and slower metabol...

In this episode I break down Dihexa, one of the most talked about compounds in the brain health and longevity space right now. I start by addressing something I know longtime listeners are going to wonder immediately. I talk a lot on this podcast about how most peptides do not work when taken orally. So why does Dihexa come as a capsule. I explain exactly why in plain language and why this is completely different from the supplement pills I always caution people about. It comes down to what kind...

In this episode, I break down Epitalon, a longevity peptide that has been studied for more than 40 years. I explain the research around telomerase and telomeres, how Epitalon may relate to cellular aging, sleep and circadian rhythms, hormone timing, immune support, and cellular protection. I also discuss the FDA advisory committee review of Epitalon in July 2026 and where the research stands today, including what we know and what we still don't know.

In this episode I cover Tesamorelin, one of the most research backed peptides I have ever talked about on this podcast. Unlike most compounds in this space Tesamorelin has full FDA approval and two large Phase 3 human clinical trials behind it showing real measurable reductions in visceral fat, the deep internal fat around your organs that is the most dangerous kind and the hardest to lose. I explain what it is, how it works, and why the fact that it works with your body's own natural growth hor...

What should you know before getting a peptide injection at a wellness clinic or med spa? In Part 2 of this conversation, Michele talks about prescriptions, medical oversight, potential red flags, and three important questions to ask before allowing anyone to give you a peptide injection.

I have been getting messages from people who are mixing and injecting peptides on their own with no doctor involved, no guidance on how to reconstitute them correctly, and no idea what dose is appropriate for their situation. This episode is for them. And for anyone who is considering going that route. I am not here to judge anyone. I am here to give you the information you may have not been given before you started. In this episode I explain what research grade actually means and why the not fo...

Getting on a GLP-1 is just the beginning. What you do while you are on it matters enormously for your results and your long term health. In this episode I cover the five most important things for anyone who is on or considering a GLP-1. I’m discussing protein and why it is the most critical thing to prioritize and what the published research actually says about how much you need to protect your muscle. Strength training and why without it you risk losing the wrong kind of weight. Hydration and ...

This is one of the most personal episodes I have done. I have Lyme disease. I was diagnosed in my late 40s completely by accident through a routine eye exam with a new doctor who noticed something previous exams had missed. Specialists. A CT scan. Comprehensive blood tests. And buried in those results was Lyme disease, something nobody had even been looking for. The eye and the Lyme turned out to be completely unrelated. My infectious disease doctor confirmed that. And I was told I had probably ...

In this episode I break down Semax, a peptide that has been used clinically in Russia for decades and is now being talked about seriously in the longevity and cognitive health space. And yes it is a nasal spray. I explain exactly why in plain language and the science behind it is genuinely fascinating. The nose to brain delivery pathway is real and it is the reason this specific compound works the way it does. I cover what the research actually shows for focus, memory, mental endurance, mood, mo...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down PT-141 and why it is one of the most legitimately researched peptides I have ever covered on this podcast. It has full FDA approval under the brand name Vyleesi, the first non-hormonal treatment ever approved for female sexual desire disorder, backed by two Phase 3 clinical trials in over 1,200 ...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. Today something happened that I have never seen before in this space. I watched live as a formal FDA advisory committee voted in favor of four of the most researched peptides in the wellness and longevity world for inclusion on the official list that creates a clear legal compounding pathway through licensed pharmacies...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. This podcast has always been about education. But the question I get asked more than almost anything else is where do I actually get my peptides and who do I trust. So today I am finally doing a full episode on it. I walk through what I looked for before I trusted anyone with my health, why the difference between research g...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down Methylene Blue, a pharmaceutical grade compound that has been used in medicine since the 1890s and is now one of the most interesting things being studied in the longevity and brain health space. Yes it was originally a textile dye. Yes it is now being studied in real published human trials...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down something every single woman in midlife has experienced. Why your body just stops responding the way it used to. You are doing everything right and nothing is working the way it did in your thirties. Today I explain exactly why. I walk through what is actually happening inside your body after 40...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I go deeper on GLP-1s, specifically the conversation everyone is having right now about microdosing tirzepatide and semaglutide. Not for dramatic weight loss. For metabolic health, inflammation, cardiovascular protection, and brain health. And yes, people do lose weight on it too, which makes it a real optio...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down sermorelin, the peptide that does not do the job itself, it tells your body to do the job. Specifically it signals your pituitary gland to release its own growth hormone the natural way. Growth hormone declines roughly 14 percent every decade after your 30s and that decline is connected to so mu...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down KLOW, a four peptide blend combining BPC-157, TB-500, GHK-Cu, and KPV into one single formula. If you have heard my episodes on GHK-Cu and BPC-157 plus TB-500 and wondered what it would look like to bring it all together, this episode is for you. I cover what each ingredient does in plain langua...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down Melanotan II, a man-made peptide designed to copy a signal your body already knows how to receive, that activates a whole network of switches throughout your body and your brain. I’m explaining it like you’re in 5th grade. What it actually is, where the real research lives, and why I’m being upf...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down glutathione, the tiny peptide researchers call the “master antioxidant” that your body has been making on its own your entire life. Today I’m covering what it actually is, why levels drop as we get older, and what the research says, explained like you’re in 5th grade. We get into how glutathione...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down DSIP, also known as Delta Sleep Inducing Peptide, the tiny peptide everyone is asking me about for sleep. Today I’m covering what it actually is, why people are so curious about it, and what the research says, explained like you’re in 5th grade. We get into how DSIP works as a natural “sleep sig...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down NAD+, the tiny helper molecule inside every single one of your cells that makes energy possible, and the one your body loses nearly half of by the time you’re 50. Plot twist: NAD+ is not technically a peptide. I’m explaining what it actually is, why it gets grouped in with peptides anyway, why ...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down BPC-157 and TB-500. The two peptides that people talk about together so often they’ve earned the nickname “the recovery power couple.” Explained like you’re in 5th grade. We get into what each peptide actually does (one’s the construction crew, one’s the traffic director), why people stack them...